Preparation and properties of chiral 4-pyrrolidinopyridine (PPY) analogues with dual functional side chains
書誌事項
- 公開日
- 2003-02
- 権利情報
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- https://www.elsevier.com/tdm/userlicense/1.0/
- DOI
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- 10.1016/s0040-4039(03)00021-2
- 公開者
- Elsevier BV
この論文をさがす
説明
Abstract Chiral 4-pyrrolidinopyridine analogues 8 – 13 with two distinct functional side chains at C(2) and C(4) of the pyrrolidine ring were prepared from 4-hydroxy- l -proline. We examined desymmetrization of meso -1,3-cyclohexanediol through enantioselective acylation using these catalysts and found that introduction of a C(4)-side chain was effective for improving both the chemo- and enantioselectivity of acylation.
収録刊行物
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- Tetrahedron Letters
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Tetrahedron Letters 44 (8), 1545-1548, 2003-02
Elsevier BV
