Innovative Strategies for Hypoxic‐Tumor Photodynamic Therapy

  • Xingshu Li
    Department of Chemistry and Nano Science Ewha Womans University Seoul 120–750 Korea
  • Nahyun Kwon
    Department of Chemistry and Nano Science Ewha Womans University Seoul 120–750 Korea
  • Tian Guo
    Department of Chemistry and Nano Science Ewha Womans University Seoul 120–750 Korea
  • Zhuang Liu
    Institute of Functional Nano&Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices Soochow University Suzhou Jiangsu 215123 China
  • Juyoung Yoon
    Department of Chemistry and Nano Science Ewha Womans University Seoul 120–750 Korea

説明

<jats:title>Abstract</jats:title><jats:p>Despite its clinical promise, photodynamic therapy (PDT) suffers from a key drawback associated with its oxygen‐dependent nature, which limits its effective use against hypoxic tumors. Moreover, both PDT‐mediated oxygen consumption and microvascular damage further increase tumor hypoxia and, thus, impede therapeutic outcomes. In recent years, numerous investigations have focused on strategies for overcoming this drawback of PDT. These efforts, which are summarized in this review, have produced many innovative methods to avoid the limits of PDT associated with hypoxia.</jats:p>

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