From the Department of Medicine (J.E.S.), University of Queensland, Brisbane, Australia; School of Human Movement Studies (J.E.S., J.S.C.), Brisbane, Australia; Clinical Pharmacology Unit (C.M.M., I.B.W.), University of Cambridge, Addenbrooke’s Hospital, Cambridge, United Kingdom; and the Department of Cardiology (R.C., P.P., J.R.C.), University of Wales College of Medicine, University Hospital, Cardiff, United Kingdom. (At 2008-04)