Department of Medicine, Cardiology Division, and Department of Surgery, Division of Cardiac Surgery, The Johns Hopkins Hospital, Blalock 618, 600 North Wolfe Street, Baltimore, MD 21287; Institute for Cell Engineering, Broadway Research Building, Suite 651, 733 North Broadway,The Johns Hopkins University School of Medicine, Baltimore, MD 21205; and Osiris Therapeutics, 2001 Aliceanna Street, Baltimore, MD 21231-3043 (At 2005-08)