Department of Medicinal Chemistry, Department of HTS and Molecular Pharmacology and Department of Molecular Structure, One Kendall Square, Building 1000, Cambridge, Massachusetts 02139, and Department of Inflammation, Department of Pharmaceutics, and Department of Pharmacokinetics and Drug Metabolism, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, California 91320-1799(2006-08-22時点)