From the Division of Cardiovascular Medicine, Department of Internal Medicine (N.S., T.Y., T.T., M.S., R.S., M.T., N.E., M.Y., K.H., S.K.), Kobe University Graduate School of Medicine, Kobe, Japan; the Department of Geriatrics (A.F., T.H.), Nagoya University Graduate School of Medicine, Nagoya, Japan; the Department of Pharmacology (K.I., T.N.), School of Medicine, Fujita Health University, Aichi, Japan; and the Department of General Medicine (S.K.), Nakatsu Saiseikai Hospital, Osaka, Japan. (At 2008-06)