From the Department of Pharmacology (T.Y., T.F., K.Y., A.H., H.K., O.T., Y. Okada, C.-Y.X., K.T., S.K., F.U.), the Department of Biochemistry (T.T.), and the First Department of Internal Medicine (T.S., Y. Ohsaki, K.K.), Asahikawa Medical College, Midorigaoka-Higashi, Asahikawa, and the Department of Pharmacology, Kyoto University Faculty of Medicine, Kyoto (S.N.), Japan.(2003-11-11時点)