Identification, determination and biological evaluation of novel styrene trimer in polystyrene container.

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  • YAMADA Toshihiro
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • HIRANO Satoshi
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • KOBAYASHI Kazuhiro
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • SAKURAI Takanobu
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • TAKAKI Ichinari
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • TANAKA Masaharu
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • NAGAO Yasuhiro
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • AZUMA Yukimasa
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • DATE Katsuhiro
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • OHNO Katsutoshi
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • CHIBA Masaru
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055
  • NOBUHARA Yoichi
    Central Research Institute,Nissin Food Products Co.,Ltd.,2247,Noji,Kusatsu-shi,Shiga 525-0055

Bibliographic Information

Other Title
  • ポリスチレン容器中に存在する新規スチレントリマーの同定，定量及び生物学的評価
  • ポリスチレン ヨウキ チュウ ニ ソンザイ スル シンキ スチレントリマー ノ ドウテイ テイリョウ オヨビ セイブツガクテキ ヒョウカ

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Description

The presence of unidentified styrene trimers(NST-12-1 and NST-12-2)was confirmed in the eluted substance of polystyrene.Both compounds were two diastereomers of 1-phenyl-4-(2-phenylethyl)tetralin, which were proved to be the 1, 4-cis(NST-12-1)and 1, 4-trans(NST-12-2)configuration by instrumental analysis and chemical synthesis.The content and miglation of NST-12 in polystyrene products were determined by GC/MS(SIM).Furthermore, the endocrine-disrupting effects of NST-12 were tested by in vivo and in vitro assays.It appeared that NST-12 has no such effects.

Journal

  • BUNSEKI KAGAKU

    BUNSEKI KAGAKU 49 (7), 493-501, 2000

    The Japan Society for Analytical Chemistry

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