Metabolism of Odd-numbered Fatty Acids and Even-numbered Fatty Acids in Mouse
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- Gotoh Naohiro
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
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- Moroda Koichiro
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
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- Watanabe Hiroyuki
- Department of Health Science, Kochi Women’s University
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- Yoshinaga Kazuaki
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
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- Tanaka Miho
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
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- Mizobe Hoyo
- Tsukishima Foods Industry Co. Ltd.
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- Ichioka Kenji
- Tsukishima Foods Industry Co. Ltd.
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- Tokairin Shigeru
- Tsukishima Foods Industry Co. Ltd.
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- Wada Shun
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
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説明
Fatty acids are converted into energy via beta-oxidation. Although almost all natural occurring fatty acids are even-numbered, there are some odd-numbered fatty acids too. The details of the metabolism rate of odd-numbered fatty acids, however, are not clear. In the present study, we simultaneously administered a triacylglycerol containing four types of labeled even-numbered (palmitic acid and stearic acid) and odd-numbered (pentadecanoic acid and heptadecanoic acid) fatty acids to mice to compare the rates of their metabolism. The rates of metabolism were evaluated based on the accumulation of the labeled fatty acids in the small intestine epithelium, liver, and epididymal fat. Odd-numbered fatty acids accumulated mainly in the epididymal fat. In contrast, there was no accumulation of even-numbered fatty acids observed in the small intestine epithelium, liver, or epididymal fat. These results suggest that odd-numbered fatty acids might not be favorable substrates for beta-oxidation-related enzymes.<br>
収録刊行物
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- Journal of Oleo Science
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Journal of Oleo Science 57 (5), 293-299, 2008
公益社団法人 日本油化学会
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詳細情報 詳細情報について
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- CRID
- 1390001204090780928
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- NII論文ID
- 130000055403
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- NII書誌ID
- AA11503337
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- COI
- 1:STN:280:DC%2BD1c3jsVaisQ%3D%3D
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- ISSN
- 13473352
- 13458957
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- NDL書誌ID
- 9461139
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- PubMed
- 18391478
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可