Increase in Deformability of Human Erythrocytes through the Action of β-Lysophospholipid Rich in <I>n</I>-3 Polyunsaturated Fatty Acid Content

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  • <I>n</I>-3系多価不飽和脂肪酸高含有β-リゾリン脂質によるヒト赤血球変形能の増進作用
  • n-3系多価不飽和脂肪酸高含有β-リゾリン脂質によるヒト赤血球変形能の増進作用
  • Increase in Deformability of Human Eryt

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Abstract

Lysophosphatidylcholine (LPC) that binds to docosahexaenoic acid (DHA) at the sn-2 position (β-DHA-LPC) was prepared by the Lipozyme mediated selective partial hydrolysis of DHA-enriched egg yolk lecithin. The β-DHA-LPC was found to be rapidly incorporated into erythrocyte cells and increase their deformability at 5μM/erythrocyte.

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