Preparation of Nanopcapsules with Alginate/Polylysine Complex Wall

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  • ABE Masahiko
    Faculty of Science and Technology, Tokyo University of Science Research Center of Advanced Materials, Tokyo University of Science
  • TANAKA Kensuke
    Faculty of Science and Technology, Tokyo University of Science
  • NAKAYAMA Ai
    Faculty of Science and Technology, Tokyo University of Science
  • KONDO Tamotsu
    Faculty of Science and Technology, Tokyo University of Science
  • TSUCHIYA Koji
    Faculty of Science and Technology, Tokyo University of Science
  • TANTAYAKOM Veerapat
    Faculty of Science and Technology, Tokyo University of Science
  • OHKUBO Takahiro
    Research Center of Advanced Materials, Tokyo University of Science
  • SAKAI Hideki
    Faculty of Science and Technology, Tokyo University of Science Research Center of Advanced Materials, Tokyo University of Science

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  • Preparation of Nanocapsules with Alginate/Polylysine Complex Wall

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This paper deals with a novel preparation method of nanocapsules with alginate/polylysine complex wall. The preparation method consisted of the following steps: dispersion of an aqueous sodium alginate solution into cyclohexane to give a W/O emulsion, preparation of calcium alginate gel beads by adding the emulsion into a calcium aerosol OT solution in cyclohexane, and alginate/polylysine complex wall formation on the surface of calcium alginate beads by adding the beads into an aqueous poly-L-lysine solution. The size of alginate/polylysine complex capsules thus prepared was found to be 100-500 nm. Moreover, an attempt was made to prepare much smaller capsules using a laboratory-made apparatus for electrocapillary emulsification and the capsule size could be reduced to about 40 nm.<br>

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