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- Sakai Hideki
- Faculty of Science and Technology, Tokyo University of Science Research Institute of Science and Technology, Tokyo University of Science
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- Sekita Ayasa
- Faculty of Science and Technology, Tokyo University of Science
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- Tanaka Keisuke
- Faculty of Science and Technology, Tokyo University of Science
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- Sakai Kenichi
- Faculty of Science and Technology, Tokyo University of Science
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- Kondo Tamotsu
- Faculty of Science and Technology, Tokyo University of Science
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- Abe Masahiko
- Faculty of Science and Technology, Tokyo University of Science Research Institute of Science and Technology, Tokyo University of Science
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説明
This article reports the preparation and properties of nanosized biodegradable polymer capsules synthesized using the electrocapillary emulsification method. The biodegradable polymers used were poly(ε-caprolactone) (PCL), which is a highly biodegradable and biocompatible polymer, and poly(lactide-co-glycolic acid) (PLGA). While the size of the capsules prepared using PCL alone was in the micrometer range, it decreased with an increase in the amount of PLGA added to PCL and eventually reached the nanometer level. When the electrocapillary emulsification applied potential was 2000 V, the sizes of the capsules (PCL:PLGA = 5:5) ranged from 50 to 80 nm. The percentage of glucose trapped in the PCL/PLGA nanocapsules was higher than 80% and the duration of glucose release from the nanocapsules was about two times longer than that from PCL capsules.
収録刊行物
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- Journal of Oleo Science
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Journal of Oleo Science 60 (11), 569-573, 2011
公益社団法人 日本油化学会
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詳細情報 詳細情報について
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- CRID
- 1390001204091648384
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- NII論文ID
- 130001373806
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- NII書誌ID
- AA11503337
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- ISSN
- 13473352
- 13458957
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- NDL書誌ID
- 11279280
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可