Erythrocytes Carotenoids after Astaxanthin Supplementation in Middle-Aged and Senior Japanese Subjects

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  • Miyazawa Taiki
    Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University
  • Nakagawa Kiyotaka
    Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University
  • Kimura Fumiko
    Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University
  • Satoh Akira
    Life Science Institute, Yamaha Motor Company Limited
  • Miyazawa Teruo
    Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University

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A randomized, double-blind human trial was conducted to assess the effect of 4- or 12-week astaxanthin supplementation (1 or 3 mg/day) on the carotenoid compositions of erythrocytes in Japanese middle-aged and senior subjects. Erythrocyte astaxanthin concentrations after 4- or 12-weeks of supplementation (3 mg/day) was significantly higher than after placebo or 1 mg astaxanthin supplementations. No differences were observed in either the carotenoid compositions or the phospholipid hydroperoxide concentrations in erythrocytes after astaxanthin intake in both the 1 and 3 mg/day groups.

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