Interaction between .ALPHA.-Linolenic Acid-Enriched Oil and ACE Inhibitor Concerning the Decrease in Blood Pressure in SHR
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- Matsuo Tatsuhiro
- Faculty of Agriculture, Kagawa University
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- Yagi Kanako
- Faculty of Agriculture, Kagawa University
Bibliographic Information
- Other Title
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- Interaction between α-linolenic acid-enriched oil and ACE inhibitor concerning the decrease in blood pressure in SHR
- Interaction between a linolenic acid enriched oil and ACE inhibitor concerning the decrease in blood pressure in SHR
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Description
α-Linolenic acid (ALA) has been reported to exhibit an antihypertensive effect. Angiotensin-converting enzyme inhibitor (ACEI) is also an antihypertensive agent. We evaluated the interaction between ALA-enriched oil (test oil) and ACEI concerning the decrease in blood pressure by administering test oil, ACEI, or test oil + ACEI to 7-week-old spontaneously hypertensive rats (SHR). After administration, the systolic pressure decreased significantly in all groups compared with the level before administration, but the diastolic pressure decreased significantly only in the test oil + ACEI group. No significant difference was noted in systolic or diastolic pressure among the 3 groups. These results suggest that the interaction between ALA-enriched oil and ACEI is limited. Our study suggested the safety of consuming foods containing a large amount of ALA in combination with hypotensive agents.<br>
Journal
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- Journal of Oleo Science
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Journal of Oleo Science 57 (1), 11-14, 2008
Japan Oil Chemists' Society
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Keywords
Details 詳細情報について
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- CRID
- 1390001204093010560
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- NII Article ID
- 130000055443
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- NII Book ID
- AA11503337
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- ISSN
- 13473352
- 13458957
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- NDL BIB ID
- 9304337
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed