Effects of Oil and Drug Concentrations on Droplets Size of Palm Oil Esters (POEs) Nanoemulsion

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  • Sakeena M. H. F.
    Department of Pharmaceutical Technology, School of Pharmaceutical Sciences, Universiti Sains Malaysia Department of Pharmacy, Faculty of Allied Health Sciences, University of Peradeniya
  • Elrashid S. M.
    Department of Pharmaceutical Technology, School of Pharmaceutical Sciences, Universiti Sains Malaysia
  • Munavvar A. S.
    Department of Physiology, School of Pharmaceutical Sciences, Universiti Sains Malaysia
  • Azmin M. N.
    Department of Pharmaceutical Technology, School of Pharmaceutical Sciences, Universiti Sains Malaysia

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Abstract

Aim of the present work is to study the effects of oil and drug concentrations on droplets size of a nanoemulsion. Newly introduced oil, palm oil esters (POEs) by Universiti Putra Malaysia researchers was selected for the oil phase of the nanoemulsion, because the oil was reported to be a good vehicle for pharmaceutical use. Nanoemulsions were prepared with different concentrations of oil and drug and their effects on droplets size were studied by laser scattering spectroscopy (Nanophox). The results of droplets size analysis shows the droplets size increase with increasing concentration of oil and drug concentrations. It can be concluded from this study, that oil and drug concentrations have an effect on the droplets size of POEs nanoemulsion system.

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