書誌事項
- タイトル別名
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- Low-density/high-density lipoprotein cholesterol ratio affects fibrinolytic activity during strenuous exercise
- テイブンシ/コウブンシ リポタンパク コレステロールヒ ワ コウキョウド ウンドウ ゴ ノ センヨウ カッセイ ニ エイキョウ オ アタエル
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Introduction: An increase in the level of plasminogen activator inhibitor-1 (PAI-1) may be a factor related to coronary artery disease, which can be a cause of sudden death during exercise. The aim of this study was to evaluate whether a difference in the ratio of low-density (LDL-C) to high-density (HDL-C) lipoprotein cholesterol (L/H ratio) might affect the PAI-1 level during acute strenuous exercise.<br> Subjects and Methods: Thirteen healthy trained men aged 19 to 23 years participated. Seven were categorized as having a L/H ratio of <2.0 (L/H <2.0 group), and 6 as having a L/H ratio of ≧2.0 (L/H ≧2.0 group). Venous blood samples were collected from the subjects before and after they had performed the Cooper 12-min test (running as far as possible within 12 min). LDL-C concentration (mg/dL), HDL-C concentration (mg/dL), and PAI-1 level (ng/mL) were measured using blood samples.<br> Results: The PAI-1 level before (30.4±1.9 ng/mL) and after (25.8±3.4 ng/mL) exercise did not change significantly in the L/H <2.0 group, whereas it increased significantly in the L/H ≧2.0 group (41.1±10.0 ng/mL to 61.8±11.7 ng/mL, p<0.05).<br> Conclusions: The present study revealed that the PAI-1 level increased significantly after acute strenuous exercise only in the high L/H ratio (≧2.0) group.<br>
収録刊行物
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- 体育学研究
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体育学研究 59 (2), 453-463, 2014
一般社団法人 日本体育・スポーツ・健康学会
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詳細情報 詳細情報について
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- CRID
- 1390001204101156096
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- NII論文ID
- 130004801309
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- NII書誌ID
- AN00409623
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- ISSN
- 18817718
- 04846710
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- NDL書誌ID
- 026002435
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
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- 使用不可