ChemInform Abstract: THE REACTION OF CYANOGUANIDINE WITH FORMALDEHYDE. I. HYDROXYMETHYLATION AND METHOXYMETHYLATION OF CYANOGUANIDINE

DOI DOI PDF 被引用文献6件 参考文献4件 オープンアクセス

書誌事項

タイトル別名
  • The reaction of cyanoguanidine with formaldehyde. I. Hydroxymethylation and methoxymethylation of cyanoguanidine.

この論文をさがす

説明

In order to examine the reactivity of cyanoguanidine (CG) with formaldehyde, CG was first hydroxymethylated, then methoxylated, and finally exhaustively hydroxymethylated with a large excess of formaldehyde. 4-Cyanoimino-3-methoxymethylperhydro-1,3,5-oxadiazine was isolated as a major reaction product of 1,3-bis(methoxymethyl)-2-cyanoguanidine with formaldehyde. This product is an adduct of 3 mol of formaldehyde per mole of CG and a six-membered cyclic ether. Minor products were further methoxylated and 3,5-bis(methoxymethyl)-4-methoxymethyl(carbamoylimino)perhydro-1,3,5-oxadiazine was isolated. This is an adduct of 2 mol of formaldehyde to the amidinated product derived from the major product by the hydration of the cyano group. The ring structure of perhydro-1,3,5-oxadiazine was so stable that it could not be decomposed under acidic conditions if the methoxymethyl groups were fully acid-hydrolyzed.

収録刊行物

被引用文献 (6)*注記

もっと見る

参考文献 (4)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ