A convenient synthesis of cholesta-1,5,7-trien-3.BETA.-ol.
-
- Tachibana Yoji
- Central Research Laboratory, Nisshin Flour Milling, Co., Ltd.
Bibliographic Information
- Other Title
-
- A Convenient Synthesis of Cholesta-1,5,7-trien-3β-ol
Description
Cholesta-4,6-dien-3β-ol (4) was obtained selectively by the dehydrobromination of 7-bromocholesterol with a base in the presence of a catalytic amount of tetrabutylammonium bromide. The oxidation of 4 with 2,3-dichloro-5,6-dicyano-p-benzoquinone gave cholesta-1,4,6-trien-3-one (7). Treatment of 7 with isopropenyl acetate under acidic conditions afforded 3-acetoxy-1,3,5,7-cholestatetraene, which was reduced with calcium borohydride to yield cholesta-1,5,7-trien-3β-ol (2).
Journal
-
- Bulletin of the Chemical Society of Japan
-
Bulletin of the Chemical Society of Japan 59 (11), 3702-3704, 1986
The Chemical Society of Japan
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390001204127332608
-
- NII Article ID
- 130001983335
-
- ISSN
- 13480634
- 00092673
-
- Text Lang
- en
-
- Data Source
-
- JaLC
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed
