Cytotoxic substances from two species of Japanese sea hares: chemistry and bioactivity
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- YAMADA Kiyoyuki
- Professor Emeritus, Nagoya University
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- OJIKA Makoto
- Graduate School of Bioagricultural Sciences, Nagoya University
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- KIGOSHI Hideo
- Graduated School of Pure and Applied Sciences, University of Tsukuba
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- SUENAGA Kiyotake
- Faculty of Science and Technology, Keio University
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Abstract
From the sea hares belonging to two genera, Aplysia and Dolabella, a variety of new cytotoxic substances were isolated as minute constituents: their chemical structures were determined and their cytotoxicity was evaluated. Regarding the highly cytotoxic substances, further chemical and biological studies were performed that included their asymmetric chemical synthesis and elucidation of biological characteristics such as antitumor activity.<br><br>(Communicated by Satoshi OMURA, M.J.A.)
Journal
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- Proceedings of the Japan Academy, Series B
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Proceedings of the Japan Academy, Series B 86 (3), 176-189, 2010
The Japan Academy
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Keywords
Details 詳細情報について
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- CRID
- 1390001204146704256
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- NII Article ID
- 130000264072
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- NII Book ID
- AA00785485
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- ISSN
- 13492896
- 03862208
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- NDL BIB ID
- 10621854
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed