A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization
-
- HAMAMOTO TETSUO
- Department of Agricultural Chemistry, Tokyo University
-
- GUNJI SHIGEMICHI
- Department of Agricultural Chemistry, Tokyo University
-
- TSUJI HIROAKI
- Department of Agricultural Chemistry, Tokyo University
-
- BEPPU TERUHIKO
- Department of Agricultural Chemistry, Tokyo University
書誌事項
- タイトル別名
-
- Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization.
- I. TAXONOMY OF THE PRODUCING STRAIN AND THEIR FERMENTATION, PURIFICATION AND CHARACTERIZATION
この論文をさがす
説明
A strain of Streptomyces was found to produce new antifungal antibiotics. The active compounds were purified and separated into two substances named leptomycin A and B by high performance liquid chromatography. The molecular formulae of leptomycins A and B are C32H46O6 and C33H48O6 respectively, and physicochemical and biological properties of them are very similar to each other. Leptomycins A and B exhibit strong inhibitory activity against Schizosaccharomyces and Mucor.
収録刊行物
-
- The Journal of Antibiotics
-
The Journal of Antibiotics 36 (6), 639-645, 1983
公益財団法人 日本感染症医薬品協会