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NF00659A1, A2, A3, B1 and B2, Novel Antitumor Antibiotics Produced by Aspergillus sp. NF 00659. II. Structural Elucidation.
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- SUZUKI KATSUHIRO
- Applied Microbiology Research Center, Nippon Kayaku Co., Ltd.
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- KUWAHARA ATSUSHI
- Applied Microbiology Research Center, Nippon Kayaku Co., Ltd.
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- NISHIKIORI TAKAAKI
- Applied Microbiology Research Center, Nippon Kayaku Co., Ltd.
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- NAKAGAWA TAIZO
- Applied Microbiology Research Center, Nippon Kayaku Co., Ltd.
Bibliographic Information
- Other Title
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- II. Structural Elucidation
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Description
NF00659A1, A2, A3, B1 and B12, having insecticidal and antitumor activities, were isolated from a culture mycelium of Aspergillus sp. NF 00659. The novel structure of NF00659s were determined mainly by spectroscopic studies including various NMR measurements. NF00659s have a common structure which consists of acyl, α-pyrone and 4, 5-seco-tricyclic diterpene moieties.
Journal
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- The Journal of Antibiotics
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The Journal of Antibiotics 50 (4), 318-324, 1997
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION