Delaminomycins, novel nonpeptide extracellular matrix receptor antagonist and a new class of potent immunomodulator. II. Physico-chemical properties and structure elucidation of delaminomycin A.
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- UENO MITSUHIRO
- Institute for Chemotherapy, Microbial Chemistry Research Foundation
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- SOMENO TETSUYA
- Institute for Chemotherapy, Microbial Chemistry Research Foundation
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- SAWA RYUICHI
- Institute of Microbial Chemistry, Microbial Chemistry Research Foundation
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- IINUMA HIRONOBU
- Institute of Microbial Chemistry, Microbial Chemistry Research Foundation
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- NAGANAWA HIROSHI
- Institute of Microbial Chemistry, Microbial Chemistry Research Foundation
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- ISHIZUKA MASAAKI
- Institute for Chemotherapy, Microbial Chemistry Research Foundation
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- TAKEUCHI TOMIO
- Institute for Chemotherapy, Microbial Chemistry Research Foundation
書誌事項
- タイトル別名
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- II. PHYSICO-CHEMICAL PROPERTIES AND STRUCTURE ELUCIDATION OF DELAMINOMYCIN A
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説明
Delaminomycins, novel extracellular matrix receptor antagonists, have been isolated from a culture broth of Streptomyces albulus MJ202-72F3. The structure of delaminomycin A was determined to be 3-[[2-[(3E, 5E)-2, 8-dihydroxy-7-methyl-3, 5-decadienyl]-1, 6, 8-trimethyl-1, 2, 4a, 5, 6, 7, 8, 8a-octahydrol-naphthyl]carbonyl]-5-hydroxypyrrolidine-2, 4-dione by analyses of spectral properties and chemical studies.
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 46 (6), 979-984, 1993
公益財団法人 日本感染症医薬品協会