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- AOKI HATSUO
- Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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- MIYAIRI NORIMASA
- Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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- AJISAKA MUTSUYA
- Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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- SAKAI HEIICHI
- Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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Abstract
Dextrochrysin is produced in culture broths of Streptomyces calvus var. dextrochrysus, and can be isolated in crystalline form by solvent extraction and silica gel column chromatography. It is obtained as neutral yellowish brown platelets, m. p. 250-255°C and shows strong dextrorotation. It has antimicrobial activity against Gram-positive and Gram-negative bacteria, a Mycobacterium and some bacteriophages, but is highly toxic to mice. In in vivo anti-tumor test with EHRLICH carcinoma and YOSHIDA sarcoma cells it did not show a favorable effect.
Journal
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- The Journal of Antibiotics
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The Journal of Antibiotics 22 (5), 201-206, 1969
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
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Keywords
Details 詳細情報について
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- CRID
- 1390001204152666624
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- NII Article ID
- 130003498182
- 40018688390
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- NII Book ID
- AA0069330X
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- COI
- 1:CAS:528:DyaF1MXkt12isLs%3D
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- ISSN
- 18811469
- 00218820
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- NDL BIB ID
- 8510046
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- PubMed
- 4309428
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed