Studies on the antibiotics from Streptomyces spinichromogenes var.kujimyceticus-5-Some antimicrobial characteristics of kujimycin A and kujimycin B against macrolide resistant staphylococci

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  • STUDIES ON THE ANTIBIOTICS FROM <i>STREPTOMYCES SPINICHROMOGENES</i> VAR. <i>KUJIMYCETICUS.</i> III
  • STUDIES ON THE ANTIBIOTICS FROM STREPTOMYCES SPINICHROMOGENES VAR. KUJIMYCETICUS. V
  • STUDIES ON THE ANTIBIOTICS FROM STREPTOMYCES SPINICHROMOGENES VAR. KUJIMYCETICUS. III
  • THE STRUCTURE OF KUJIMYCIN A AND KUJIMYCIN B

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Kujimycins A and B obtained from the fermentation broth of Streptomyces spinichromogenes var. kujimyceticus have already been reported as neutral macrolides exhibiting activities against Gram-positive bacteria1). Recently, in the course of structural investigation, kujimycin B has been found to be identical with an authentic specimen of lankamycin. The structure of kujimycin A has been elucidated by some chemical degradation studies as lankamycin deacetylated at C-4 of arcanose.

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