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Early intermediates in the biosynthesis of ansamycins. II. Isolation and identification of proasamycin B-M1 and protorifamycin I-M1.
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- GHISALBA ORESTE
- Pharmaceuticals Division and Central Function Research of CIBA-GEIGY Limited
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- TRAXLER PETER
- Pharmaceuticals Division and Central Function Research of CIBA-GEIGY Limited
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- FUHRER HERMANN
- Pharmaceuticals Division and Central Function Research of CIBA-GEIGY Limited
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- RICHTER WILHELM J.
- Pharmaceuticals Division and Central Function Research of CIBA-GEIGY Limited
Bibliographic Information
- Other Title
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- II. ISOLATION AND IDENTIFICATION OF PROANSAMYCIN B-M1 AND PROTORIFAMYCIN I-M1
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Description
Proansamycin B-M1 and protorifamycin I-M1 were isolated as minor compounds from fermentations of the protorifamycin I producing strain Nocardia mediterranei F 1/241), identified by means of chemical and spectroscopic methods and shown to be degradation products of the hypothetical proansamycin B postulated in part I of this series of papers1) and of protorifamycin I, respectively.
Journal
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- The Journal of Antibiotics
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The Journal of Antibiotics 32 (12), 1267-1272, 1979
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION