PLEUROMUTILINS FERMENTATION, STRUCTURE AND BIOSYNTHESIS

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  • KNAUSEDER F.
    Research and Development Department, Biochemie Ges. m.b.H.
  • BRANDL E.
    Research and Development Department, Biochemie Ges. m.b.H.

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タイトル別名
  • Pleuromutilins Fermentation structure a

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Derivatives of pleuromutilin, formed during the fermentation of pleuromutilin. were isolated and their structure determined. 14-Acetyl-mutilin and mutilin as well as different unsaturated fatty acid esters of pleuromutilin were identified. The proportion of each derivative formed depends to a considerable degree on the conditions of the fermentation process. The possible biosynthetic pathways are shown.

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