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- MURAKAWA TAKEO
- Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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- KONO YOKO
- Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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- NISHIDA MINORU
- Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
この論文をさがす
説明
In the preceding paper1), we reported that an uncharacterized antimicrobial substance was recovered in samples from animals and healthy volunteers receiving ampicillin. This substance is formed also by the incubation of ampicillin with urine, serum or tissue homogenates. The factors contributing to the transformation of ampicillin were found to be relatively stable to heat, and sufficiently low in molecular weight to permit penetration of a cellophane membrane.<br> The present paper reports the results of additional experiments to elucidate the mechanism of the transformation and properties of this uncharacterized substance.
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 25 (7), 421-426, 1972
公益財団法人 日本感染症医薬品協会