IgG4-associated Multifocal Systemic Fibrosis Detected by Cancer Screening with 18F-FDG Positron Emission Tomography/Computed Tomography

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  • <SUP>18</SUP>F-FDG PET/CTがん検診で検出されたIgG4関連多発性全身性線維症

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Abstract

Serial fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG PET/CT)studies were performed with an interval of one year in a 62-year-old man with IgG4-associated multifocal systemic fibrosis(IMSF). He first underwent 18F-FDG PET/CT cancer screening, which revealed multiple 18F-FDG-avid uptakes in the pancreas, prostate, and lymph nodes in the upper mediastinum, pulmonary hila, porta hepatis, and the left iliac and inguinal regions. He was not symptomatic at this initial examination. The follow-up 18F-FDG PET/CT study showed disappearance of 18F-FDG-avid uptake foci in the pancreas despite no treatment having been administered, but demonstrated new lesions in the abdominal para-aortic region and more intense FDG uptake in the porta hepatis lesion. Serial 18F-FDG PET/CT studies might be useful in monitoring patients with IMSF, as well as evaluating the state of systemic involvement. Findings of 18F-FDG PET/CT may provide information useful for determining the optimal initiation of IMSF treatment.

Journal

  • RADIOISOTOPES

    RADIOISOTOPES 59 (3), 173-177, 2010

    Japan Radioisotope Association

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