ChemInform Abstract: Confluentic Acid (Ia) and 2′‐O‐Methylperlatolic Acid (Ib), Monoamine Oxidase B Inhibitors in a Brazilian Plant, Himatanthus sucuuba.
書誌事項
- タイトル別名
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- Confluentic Acid and 2'-O-Methylperlatolic Acid, Monoamine Oxidase B Inhibitors in a Brazilian Plant, Himatanthus sucuuba.
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説明
Monoamine oxidase B (MAO-B) inhibitors were isolated from the bark of a Brazilian plant, Himatanthus sucuuba (SPR.). Assignments of the 1H-and 13C-NMR data using two dimensional (2D)-NMR techniques showed the active components to be known lichen depsides, confluentic acid (1) and 2'-O-methylperlatolic acid (2). The depside (1) showed selective inhibition of MAO-B with IC50 value of 0.22μM.
収録刊行物
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- ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ
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ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ 42 (6), 1198-1201, 1994
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001204160673024
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- NII論文ID
- 110003631111
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- NII書誌ID
- AA00602100
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- COI
- 1:CAS:528:DyaK2cXlslGhsLk%3D
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- ISSN
- 13475223
- 15222667
- 00092363
- 09317597
- http://id.crossref.org/issn/00092363
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- PubMed
- 8069971
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可