A new route to 4-unsubstituted .BETA.-lactams through ureidomethylation of ketene silyl acetals.

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α-Ureidomethylated carboxylates were obtained by the reaction of ketene silyl acetals with benzyl N-(chloromethyl) carbamates in the presence of titanium tetrachloride. Successive hydrogenolysis over palladium-on-charcoal followed by treatment with lithium diisopropylamide gave β-lactams.

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