Fusarielin A as an Anti-angiogenic and Anti-proliferative Agent: Basic Biological Characterization
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- Fujimoto Haruka
- Institute of Molecular & Cellular Biosciences, The University of Tokyo
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- Aoyama Hiroshi
- Institute of Molecular & Cellular Biosciences, The University of Tokyo
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- Noguchi-Yachide Tomomi
- Institute of Molecular & Cellular Biosciences, The University of Tokyo
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- Hashimoto Yuichi
- Institute of Molecular & Cellular Biosciences, The University of Tokyo
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- Kobayashi Hisayoshi
- Institute of Molecular & Cellular Biosciences, The University of Tokyo
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Abstract
Fusarielin A shows anti-angiogenic activity in the human umbilical vein endothelial cell (HUVEC) tube formation assay. Structural development studies indicated the importance of the hydroxyl groups in this molecule. A 3H-labeled derivative and a fluorescent affinity-labeling agent were prepared and used to examine the cellular distribution and biological behavior of fusarielin A.
Journal
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- Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin 56 (3), 298-304, 2008
The Pharmaceutical Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390001204169011712
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- NII Article ID
- 110006622632
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- NII Book ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL BIB ID
- 9394454
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed
