Medicinal flowers (16) New dammarane-type triterpene tetraglycosides and gastroprotective principles from flower buds of Panax ginseng
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- Yoshikawa Masayuki
- Kyoto Pharmaceutical University
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- Sugimoto Sachiko
- Kyoto Pharmaceutical University
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- Nakamura Seikou
- Kyoto Pharmaceutical University
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- Sakumae Hayaka
- Kyoto Pharmaceutical University
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- Matsuda Hisashi
- Kyoto Pharmaceutical University
書誌事項
- タイトル別名
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- Medicinal Flowers. XVI. New Dammarane-Type Triterpene Tetraglycosides and Gastroprotective Principles from Flower Buds of Panax ginseng
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説明
The oligoglycoside fraction from the flower buds of Panax ginseng C. A. MEYER (Araliaceae) was found to show protective effects on ethanol-induced gastric mucosal lesions in rats. From the oligoglycoside fraction, new dammarane-type triterpene tetraglycosides, floralginsenosides M, N, O, and P, were isolated together with the major oligoglycosides ginsenoside Rd and Re. The structures of the new floralginsenosides were elucidated on the basis of chemical and physicochemical evidence. Ginsenoside Rd (protopanaxadiol 3,20-O-bisdesmoside) exhibited inhibitory effects on ethanol- and indomethacin-induced gastric mucosal lesions in rats.
収録刊行物
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- ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ
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ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ 55 (7), 1034-1038, 2007
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001204169534848
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- NII論文ID
- 110006317168
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- NII書誌ID
- AA00602100
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- COI
- 1:STN:280:DC%2BD2szos1ehsA%3D%3D
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 8783980
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- PubMed
- 17603196
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- 本文言語コード
- en
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