Polycyclic N-Heterocyclic Compounds. Part 59: Rearrangement Reactions of Fused Tricyclic 3-(2-Bromoethyl)pyrimidin-4(3H)-ones with Primary Amines via a Dimroth-Type Rearrangement
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- Okuda Kensuke
- Gifu Pharmaceutical University
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- Ohtomo Hiromi
- Faculty of Pharmaceutical Sciences, Okayama University
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- Tanaka Fumiaki
- Faculty of Pharmaceutical Sciences, Okayama University
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- Hirota Takashi
- Faculty of Pharmaceutical Sciences, Okayama University
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- Sasaki Kenji
- Faculty of Pharmaceutical Sciences, Okayama University
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説明
Reaction of some fused tricyclic 3-(2-bromoethyl)pyrimidin-4(3H)-ones with primary alkyl amines gave abnormal fused 3-alkyl-4-alkyliminopyrimidines via a Dimroth-type rearrangement, as well as normal substituted 3-(2-alkylaminoethyl) derivatives in methanol. This abnormal rearrangement reaction depended on reaction solvent.
収録刊行物
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- ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ
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ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ 57 (7), 755-758, 2009
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001204170320512
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- NII論文ID
- 130000124383
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 10264843
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- PubMed
- 19571428
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDLサーチ
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- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可
