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- Khalil Ashraf Taha
- Institute of Marine Resources, National Sun Yat-sen University, Taiwan
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- Shen Ya-Ching
- Institute of Marine Resources, National Sun Yat-sen University, Taiwan
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- Guh Jih-Hwa
- School of Pharmacy, College of Medicine, National Taiwan University
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- Cheng Shi-Yie
- Institute of Marine Resources, National Sun Yat-sen University, Taiwan
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抄録
Phytochemical investigation of Ixeris chinensis NAKAI (Asteraceae) has resulted in the isolation of a new guaianolide-type sesquiterpene lactone, ixerochinolide (1) as well as the related glucoside, ixerochinoside (2). In addition, the known guaianolides, 8β-hydroxy-3-oxo-guaia-4(15),10(14),11(13)-trien-1α,5α,6β,7αH-12,6-olide (8β-hydroxydehydrozaluzanin), 8β,15-dihydroxy-2-oxo-guaia-1(10),3,11(13)-trien-5α,6β,7αH-12,6-olide (lactucin), 3β,8α,10α-trihydroxy-guaia-4(15),11(13)-dien-1α,5α,6β,7αH-12,6-olide (10α-hydroxy-10,14-dihydro-desacylcynaropicrin) and 3β-D-glucopyranosyloxy-8β-(p-hydroxyphenylacetyloxy)-guaia-4(15),10(14),11(13)-trien-1α,5α,6β,7αH-12,6-olide (8-epicrepioside) were identified. The structures were determined on the basis of spectral analyses, especially 1- and 2D NMR. Compound 1 exhibited significant cytotoxicity against human PC-3 tumor cells.
収録刊行物
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- ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ
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ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ 53 (1), 15-17, 2005
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001204170879872
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- NII論文ID
- 10016651262
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 7200616
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- PubMed
- 15635221
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可