Lipoxygenase Inhibiting Constituents from Indigofera hetrantha

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  • Aziz-ur-rehman
    International Centre for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi
  • Malik Abdul
    International Centre for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi
  • Riaz Naheed
    International Centre for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi
  • Ahmad Habib
    Department of Botany, Govt. Postgraduate Jahanzeb College
  • Nawaz Sarfraz Ahmad
    International Centre for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi
  • Choudhary Muhammad Iqbal
    International Centre for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi

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A lignan and two acylphloroglucinols have been isolated from the ethyl acetate soluble fraction of the whole plant of Indigofera hetrantha. Their structures have been assigned on the basis of spectral analysis including 1D and 2D NMR techniques. Compounds 1—3 displayed promising inhibitory potential against enzyme lipoxygenase in concentration-dependent manner.

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