Anticonvulsant activity and toxicity evaluation of Cu[2] and Zn[2] metal complexes derived from triazole-quinoline ligands
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- Kulkarni Naveen Vasudev
- Department of Studies in Chemistry, Karnatak University
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- Budagumpi Srinivasa
- Department of Studies in Chemistry, Karnatak University
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- Kurdekar Gurunath Suresh
- Department of Studies in Chemistry, Karnatak University
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- Revankar Vidyanand Krishna
- Department of Studies in Chemistry, Karnatak University
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- Didagi Suresh
- Luqman College of Pharmacy
書誌事項
- タイトル別名
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- Anticonvulsant Activity and Toxicity Evaluation of Cu<sup>II</sup> and Zn<sup>II</sup> Metal Complexes Derived from Triazole-Quinoline Ligands
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A novel CuII and ZnII complexes of triazolo-quinoline derivatives were synthesized by in situ method and were characterized by the spectro-analytical methods and their pharmacological properties were evaluated. The compound C3 has exhibited promising anticonvulsant activity towards the electroshock induced seizures in Wistar rats and possesses low toxicity, providing a high safety profile.
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 58 (12), 1569-1575, 2010
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001204172406272
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- NII論文ID
- 130000405681
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 10894766
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可