Anticonvulsant activity and toxicity evaluation of Cu[2] and Zn[2] metal complexes derived from triazole-quinoline ligands

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  • Anticonvulsant Activity and Toxicity Evaluation of Cu<sup>II</sup> and Zn<sup>II</sup> Metal Complexes Derived from Triazole-Quinoline Ligands

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A novel CuII and ZnII complexes of triazolo-quinoline derivatives were synthesized by in situ method and were characterized by the spectro-analytical methods and their pharmacological properties were evaluated. The compound C3 has exhibited promising anticonvulsant activity towards the electroshock induced seizures in Wistar rats and possesses low toxicity, providing a high safety profile.

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