Butenolide and Furandione from an Endophytic Aspergillus terreus

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  • Nuclear Paulwatt
    Program in Biotechnology, Faculty of Science, Chulalongkorn University
  • Sommit Damrong
    Department of Chemistry, Faculty of Science, Mahanakorn University of Technology
  • Boonyuen Nattawut
    National Center for Genetic Engineering and Biotechnology (BIOTEC), Thailand
  • Pudhom Khanitha
    Research Centre for Bioorganic Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University

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A new butenolide, aspernolide D (1), and furandione, asperterone (2), together with four known butenolides, butyrolactones I—IV and aspernolide B, were obtained from cultures of the endophytic fungus Aspergillus terreus, isolated from the flowering plant Mammea siamensis. The structures of these compounds were elucidated by analysis of NMR spectroscopic and mass spectrometric data.

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