Three New Stereoisomers of Condensed Tannins from the Roots of Rosa multiflora

  • Park Kwan Hee
    Department of Pharmacognosy, College of Pharmacy, Chung-Ang University
  • Kim Sung Kyu
    Department of Pharmacognosy, College of Pharmacy, Chung-Ang University
  • Choi Sun Eun
    Department of Pharmacognosy, College of Pharmacy, Chung-Ang University
  • Kwon Joo Hee
    Department of Pharmacognosy, College of Pharmacy, Chung-Ang University
  • Oh Myung Hwan
    Department of Pharmacognosy, College of Pharmacy, Chung-Ang University
  • Lee Min Won
    Department of Pharmacognosy, College of Pharmacy, Chung-Ang University

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Three new stereoisomers of condensed tannins (13), and four known phenolic compounds (47) were isolated from the 80% acetone extract of the roots of Rosa multiflora Thunberg. The structures of these compounds were elucidated using 1D/2D NMR, high resolution (HR)-MS, and circular dichroism (CD) spectra. In order to evaluate their anti-oxidative and anti-inflammatory activities, their 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and inhibitory activity on nitric oxide (NO) production were determined.

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