Oppositinines A and B: New Vasorelaxant .BETA.-Carboline Alkaloids from Neisosperma oppositifolia
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- Ahmad Kartini
- Department of Chemistry, Faculty of Science and Technology, University Pendidikan Sultan Idris
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- Thomas Noel F.
- Department of Chemistry, Faculty of Science, University of Malaya
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- Hadi A. Hamid A.
- Department of Chemistry, Faculty of Science, University of Malaya
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- Mukhtar Mat Ropi
- Department of Chemistry, Faculty of Science, University of Malaya
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- Mohamad Khalit
- Department of Pharmacy, Faculty of Medicine, University of Malaya
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- Nafiah Mohd Azlan
- Department of Chemistry, Faculty of Science and Technology, University Pendidikan Sultan Idris
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- Takeya Koichi
- Tokyo University of Pharmacy and Life Sciences
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- Morita Hiroshi
- Faculty of Pharmaceutical Sciences, Hoshi University
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- Litaudon Marc
- Institut de Chimie des Substances Naturelles
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- Arai Hiroko
- Faculty of Pharmaceutical Sciences, Hoshi University
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- Awang Khalijah
- Department of Chemistry, Faculty of Science, University of Malaya
Bibliographic Information
- Other Title
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- Oppositinines A and B: new vasorelaxant β-carboline alkaloids from Neisosperma oppositifolia
- Oppositinines A and B new vasorelaxant v carboline alkaloids from Neisosperma oppositifolia
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Abstract
A phytochemical study on the bark of Neisosperma oppositifolia (Apocynaceae) yielded two new β-carboline indole alkaloids, oppositinines A (1) and B (2), together with five known alkaloids, isoreserpiline, isocarapanaubine, vobasine, 10-methoxydihydrocorynantheol-N-oxide, and ochropposinine oxindole. Structural elucidation of 1 and 2 was performed using 2D NMR methods. Oppositinines A (1) and B (2) showed potent vasorelaxant effects on the rat aorta.
Journal
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- Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin 58 (8), 1085-1087, 2010
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1390001204173138304
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- NII Article ID
- 130000299819
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- NII Book ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL BIB ID
- 10764186
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed