Researches on chemotherapeutic drugs against viruses,pt.33

DOI Web Site Web Site

書誌事項

タイトル別名
  • Researches on Chemotherapeutic Drugs against Viruses. XXXIII. Syntheses and Antiviral Activity of 1-Phenyl-3-amino-1-propanol Derivatives.

この論文をさがす

抄録

Eight compounds of 1-(p-alkylphenyl)-1-phenyl-3-(1-piperidyl)-1-propanol series, seven compounds of 1-(p-alkylphenyl)-1-phenyl-3-dimethylamino-1-propanol series, five compounds of 3-(1-piperidyl)-4'-alkylthiopropiophenone series, four compounds of 1-(p-alkylthiophenyl)-1-phenyl-3-(1-piperidyl)-1-propanol series, and seven compounds of 1-alkyl-1-(p-alkylphenyl)-3-(1-piperidyl)-1-propanol series were synthesized and their antiviral activities were tested. Several compounds of these series were found to be effective on the PR-8 strain of influenza A virus in chorioallantoic membrane, especially, 3-(1-piperidyl)-4'-octylthiopropiophenone and 1-cyclohexyl-1-(p-tolyl)-3-(1-piperidyl)-1-propanol. Several compounds of these series showed in vivo effect on the Nakayama strain of Japanese B encephalitis virus.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ