New 6-Hydroxyeunicellins from a Soft Coral Cladiella sp.

DOI Web Site Web Site 参考文献18件
  • Chen Yung-Husan
    National Museum of Marine Biology and Aquarium, Taiwan
  • Hwang Tsong-Long
    Graduate Institute of Natural Products, Chang Gung University
  • Su Yin-Di
    National Museum of Marine Biology and Aquarium, Taiwan Department of Marine Biotechnology and Resources, National Sun Yat-sen University
  • Chang Yu-Chia
    National Museum of Marine Biology and Aquarium, Taiwan Doctoral Degree Program in Marine Biotechnology, National Sun Yat-sen University and Academia Sinica
  • Chen Yu-Hsin
    National Museum of Marine Biology and Aquarium, Taiwan Department of Life Science and Institute of Biotechnology, National Dong Hwa University
  • Hong Pei-Han
    National Museum of Marine Biology and Aquarium, Taiwan Graduate Institute of Marine Biotechnology, National Dong Hwa University
  • Hu Li-Chung
    National Museum of Marine Biology and Aquarium, Taiwan Graduate Institute of Marine Biotechnology, National Dong Hwa University
  • Yen Wei-Hsuan
    National Museum of Marine Biology and Aquarium, Taiwan Graduate Institute of Marine Biotechnology, National Dong Hwa University
  • Hsu Hsin-Yin
    National Museum of Marine Biology and Aquarium, Taiwan School of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Pharmacy, China Medical University
  • Huang Shu-Jung
    National Museum of Marine Biology and Aquarium, Taiwan School of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Pharmacy, China Medical University
  • Kuo Yueh-Hsiung
    School of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Pharmacy, China Medical University Tsuzuki Institute for Traditional Medicine, College of Pharmacy, China Medical University
  • Sung Ping-Jyun
    National Museum of Marine Biology and Aquarium, Taiwan Department of Marine Biotechnology and Resources, National Sun Yat-sen University Department of Life Science and Institute of Biotechnology, National Dong Hwa University Graduate Institute of Marine Biotechnology, National Dong Hwa University Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University

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抄録

Two new 6-hydroxyeunicellin diterpenoids, cladieunicellin G (1) and 6-epi-cladieunicellin F (2), were isolated from an Indonesian octocoral Cladiella sp. The structures of eunicellins 1 and 2 were established by spectroscopic methods and 2 was found to be an epimer of the known eunicellin cladieunicellin F (3). Eunicellin 2 displayed inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.

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