Practical Synthesis of Axially Chiral Dicarboxylates via Pd-Catalyzed External-CO-Free Carbonylation

DOI Web Site Web Site PubMed 被引用文献6件 参考文献34件

書誌事項

タイトル別名
  • Practical Synthesis of Axially Chiral Dicarboxylates <i>via</i> Pd-Catalyzed External-CO-Free Carbonylation

この論文をさがす

抄録

<p>We have developed a safe and practical synthetic method for preparing axially chiral diphenyl dicarboxylates using Pd-catalyzed external-CO-free carbonylation with phenyl formate as a CO surrogate. Optimized conditions consisted of axially chiral [1,1′-binaphthalene]-2,2′-diyl ditriflate and its congeners, each easily prepared from commercially available enantiomerically pure diols, Pd(OAc)2, 1,3-bis(diphenylphosphino)propane, ethyldiisopropylamine, and no solvent. To demonstrate the potential utility of these products, this method was conducted on gram-scale and the phenyl ester products were converted to other useful compounds, and both processes were carried out without difficulty.</p>

収録刊行物

被引用文献 (6)*注記

もっと見る

参考文献 (34)*注記

もっと見る

関連プロジェクト

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ