A Rapid New Approach for the Quality Evaluation of the Folk Medicine Dianbaizhu Based on Chemometrics
-
- Liu Zizhen
- School of Chinese Pharmacy, Beijing University of Chinese Medicine
-
- Jiang Rui
- School of Chinese Pharmacy, Beijing University of Chinese Medicine
-
- Xie Meng
- School of Chinese Pharmacy, Beijing University of Chinese Medicine
-
- Xu Guanling
- School of Chinese Pharmacy, Beijing University of Chinese Medicine
-
- Liu Weirui
- School of Chinese Pharmacy, Beijing University of Chinese Medicine
-
- Wang Xiaohong
- School of Chinese Pharmacy, Beijing University of Chinese Medicine
-
- Lin Hongying
- School of Chinese Pharmacy, Beijing University of Chinese Medicine
-
- Lu Jianqiu
- Science Experiment Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine
-
- She Gaimei
- School of Chinese Pharmacy, Beijing University of Chinese Medicine
書誌事項
- タイトル別名
-
- A Rapid New Approach for the Quality Evaluation of the Folk Medicine <i>Dianbaizhu</i> Based on Chemometrics
この論文をさがす
抄録
Dianbaizhu, a folk medicine from Gaultheria leucocarpa BLUME var. yunnanensis (FRANCH.) T. Z. HSU & R. C. FANG (Ericaceae) used as an antirheumatic, has multiple plant origins and officinal parts. A rapid high-performance liquid chromatography with diode array detector (HPLC-DAD) method was established for the simultaneous determination of the characteristic ingredient methyl benzoate-2-O-β-D-glucopyranosyl(1→2) [O-β-D-xylopyranosyl(1→6)]-O-β-D-glucopyranoside and seven bioactive constituents in eight Gaultheria species. This chromatographic method is precise, accurate, and stable. Kruskal–Wallis analysis, hierarchical cluster analysis, and factor analysis were used to analyze the content of reference compounds in different Gaultheria species and officinal parts. The analyses showed significant differences (p<0.05) in Gaultheria species but few differences (p>0.05) in their medicinal parts. G. leucocarpa var. yunnanensis appeared to the best among the Gaultheria species tested for the treatment of rheumatic diseases. Taken together, the results show that this simultaneous quantification of multiple active constituents using HPLC-DAD combined with chemometrics can be reliably applied to evaluate the quality of Dianbaizhu.
収録刊行物
-
- CHEMICAL & PHARMACEUTICAL BULLETIN
-
CHEMICAL & PHARMACEUTICAL BULLETIN 62 (11), 1083-1091, 2014
公益社団法人 日本薬学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390001204178405760
-
- NII論文ID
- 130004712905
-
- NII書誌ID
- AA00602100
-
- ISSN
- 13475223
- 00092363
-
- NDL書誌ID
- 025880471
-
- PubMed
- 25366312
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可