Synthesis of Benzofuro[6,7-d]thiazoles, Benzofuro[7,6-d]thiazoles and 6-Arylaminobenzo[d]thiazole-4,7-diones as Antifungal Agent
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- Ryu Chung-Kyu
- College of Pharmacy & Graduate School of Pharmaceutical Sciences, Ewha Womans University
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- Nho Ji-Hee
- College of Pharmacy & Graduate School of Pharmaceutical Sciences, Ewha Womans University
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- Jin Guohua
- College of Pharmacy & Graduate School of Pharmaceutical Sciences, Ewha Womans University
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- Oh Sun Young
- College of Pharmacy & Graduate School of Pharmaceutical Sciences, Ewha Womans University
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- Choi Soo Jung
- College of Pharmacy & Graduate School of Pharmaceutical Sciences, Ewha Womans University
書誌事項
- タイトル別名
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- Synthesis of Benzofuro[6,7-<i>d</i>]thiazoles, Benzofuro[7,6-<i>d</i>]thiazoles and 6-Arylaminobenzo[<i>d</i>]thiazole-4,7-diones as Antifungal Agent
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抄録
Benzofuro[6,7-d]thiazoles, benzofuro[7,6-d]thiazoles and 6-arylaminobenzo[d]thiazole-4,7-diones were synthesized and tested for in vitro antifungal activity against Candida, Aspergillus species and Cryptococcus neoformans. Among them tested, many of synthesized compounds showed potent antifungal activity. The compounds 4d, 6e and 6h completely inhibited the growth of all Candida and Aspergillus species tested at the MIC level of 6.3 µg/mL. The results suggest that benzofuro[6,7-d]thiazoles and 6-arylaminobenzo[d]thiazole-4,7-diones would be promising antifungal agents.
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 62 (7), 668-674, 2014
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001204179172480
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- NII論文ID
- 130004053803
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- NII書誌ID
- AA00602100
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- COI
- 1:STN:280:DC%2BC2cnovVWhsg%3D%3D
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 025543091
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- PubMed
- 24789966
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可