Relationship between high-molecular mass intestinal alkaline phosphatase detected in blood group B and O secretors and intestinal variant alkaline phosphatase.

DOI

Bibliographic Information

Other Title
  • ＢまたはＯ型で分泌型の血液型に依存して出現する高分子小腸型アルカリ性ホスファターゼと小腸型バリアントとの関連性

Abstract

We have studied a relationship between high-molecular mass intestinal alkaline phosphatase (HIAP) found in blood group B and O secretors on 6.0% polyacrylamide disc gel electrophoresis in the presence of 1.0% TritonX-100 and the intestinal variant alkaline phosphatase (IAP-variant) on agarose gel electrophoretic method. The serum of 53 healthy subjects was tested by above two electrophoretic methods. The HIAP and IAP-variant were detected in the same subjects, and the levels of their activity were higher in serum of blood group B and O secretors. In addition, the HIAP and IAP-variant can be normalized to usual IAP by brief treatment with subtilisin or papain on respective methods. These results suggest that HIAP and TAP-variant are the same IAP isoform.

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Details 詳細情報について

  • CRID
    1390001204201888000
  • NII Article ID
    130003433527
  • DOI
    10.2198/sbk.44.135
  • ISSN
    13499785
    00319082
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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