書誌事項
- タイトル別名
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- Safety Assessment of Excessive Intake of Vinegar Drink Supplemented with Xylooligosaccharide in Normal Volunteers
- キシロオリゴトウ ハイゴウ ショクズ インリョウ ノ ケンジョウジン ニ タイスル カジョウ セッシュジ ノ アンゼンセイ シケン
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説明
A placebo-controlled, double-blind study was performed to assess the safety of excessive intake of xylooligo-saccharide-containing vinegar drinks. Forty-six volunteers with fecal frequency of less than 5 times per week were enrolled and the effects of the drink on defecation were also examined. Two-week administration of the test drink (at three times the daily recommended intake) did not affect blood pressure, hematological data, blood chemistry or urinalysis. No abnormal changes or severe adverse events related to the test drink were observed. The test drink significantly increased the fecal frequency of mildly constipated subjects but the placebo had no effect. These data indicate that the xylooligosaccharide-containing vinegar drink is safe in healthy subjects and that the drink has beneficial effects on defecation in mildly constipated subjects.
収録刊行物
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- 生活衛生
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生活衛生 51 (2), 85-91, 2007
社団法人 大阪生活衛生協会
