病原性真菌の二形性 Ｐａｒａｃｏｃｃｉｄｉｏｉｄｅｓ ｂｒａｓｉｌｉｅｎｓｉｓを中心として
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- 金綱 史至
- 京都大学医学部附属皮膚病特別研究施設
書誌事項
- タイトル別名
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- Dimorphism of pathogenic fungi, with special reference to Paracoccidioides brasiliensis.
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説明
On the basis of the biochemical and morphological studies on Paracoccidioides brasiliensis, a hypothesis for the conversion from a yeastlike (Y) form to a mycelial (M) form is proposed as follows. The synthesis of the cell wall components in the outer layer of the Y form cell wall is inhibited by environmental changes, resulting in the formation of a tunnel through which the M form extends. The microfibrils of a linear polysaccharide (chitin) in the inner layer of the weakened Y form cell wall are pressed by turgor pressure between the tunnel and expanding cytoplasm. In this condition, a part of the microfibrils is turned mechanically toward the exit of the tunnel and the synthesis of microfibrils in a more or less longitudinal orientation continues smoothly. However, in the tunnel, the synthesis of microfibrils that lie transversely to the long axis of hypha may be limited or may put a hoop on parallel longitudinal microfibrils. Out of the tunnel, a cylindrical form is maintained by the elongation of the hooped microfibrils in a longitudinal orientation in the apical region. Chitin may be synthesized isotropically in subapical region, resulting in the formation of randomly oriented microfibrils. Branched polysaccharides and proteins are interlaced with chitin and the M form is completed.
収録刊行物
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- 真菌と真菌症
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真菌と真菌症 25 (2), 102-107, 1984
日本医真菌学会
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詳細情報 詳細情報について
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- CRID
- 1390001204211047424
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- NII論文ID
- 130003671246
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- ISSN
- 18846971
- 05830516
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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