Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for the Diagnosis of Intrathoracic Lesions : Experience of a Single Academic Medical Center
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- YASUO Masanori
- Endoscopic Examination Center, Shinshu University School of Medicine, Shinshu University Hospital First Department of Internal Medicine, Shinshu University School of Medicine
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- KOBAYASHI Takashi
- First Department of Internal Medicine, Shinshu University School of Medicine Comprehensive Cancer Center, Division of Clinical Oncology, Shinshu University School of Medicine, Shinshu University Hospital
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- TOKORO Yayoi
- First Department of Internal Medicine, Shinshu University School of Medicine
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- HORIUCHI Toshimichi
- First Department of Internal Medicine, Shinshu University School of Medicine
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- ITO Michiko
- First Department of Internal Medicine, Shinshu University School of Medicine
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- KOJIMA Kazushi
- Undergraduate, School of Medicine, Shinshu University School of Medicine
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- IKEGAWA Kayoko
- First Department of Internal Medicine, Shinshu University School of Medicine
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- USHIKI Atsuhito
- First Department of Internal Medicine, Shinshu University School of Medicine
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- YAMAMOTO Hiroshi
- First Department of Internal Medicine, Shinshu University School of Medicine
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- HANAOKA Masayuki
- First Department of Internal Medicine, Shinshu University School of Medicine
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- KOIZUMI Tomonobu
- Comprehensive Cancer Center, Division of Clinical Oncology, Shinshu University School of Medicine, Shinshu University Hospital
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- YOSHIZAWA Akihiko
- Department of Laboratory Medicine, Shinshu University School of Medicine
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- HONDA Takayuki
- Department of Laboratory Medicine, Shinshu University School of Medicine
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- KUBO Keishi
- First Department of Internal Medicine, Shinshu University School of Medicine
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抄録
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has been recognized as a minimally-invasive and effective method for the diagnosis and nodal staging of lung cancer.<br>We describe our initial experience with this method, including diagnostic sensitivity, safety, importance of obtaining histological samples, and diagnostic pitfalls. We retrospectively studied 100 patients (108 consecutive procedures) with radiologically suspicious intrathoracic lesions who were investigated by EBUS-TBNA.<br>The procedures were performed between January 2005 and December 2011 at our institute. Adequate sampling value was 91.7%. Total diagnostic yield was 68.5% (74/108). In diagnosed subjects, malignancy and benign disease were identified in 68 and 6 cases, respectively. Diagnostic yield was relatively high in malignancy (88.3%), and poor in benign (19.4%). In the subgroup of malignant subjects, the diagnostic yield was higher in lung cancer (96.2%) than in other malignancies (72.0%) but, the difference disappeared if malignant lymphoma was excluded. No major complications were associated with the procedure.<br>EBUS-TBNA is useful in accessing the circumference of the central airway tumor for diagnosis. Compared with previous studies, the diagnostic yield of mediastinal lymphoma and benign lesions is worse in our laboratory. Adequate tissue sampling and preparation are needed for the definitive diagnosis of malignant lymphoma and benign lesions.
収録刊行物
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- 信州医学雑誌
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信州医学雑誌 60 (5), 249-255, 2012
信州医学会
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詳細情報 詳細情報について
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- CRID
- 1390001204211567744
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- NII論文ID
- 130004551860
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- NII書誌ID
- AN00120815
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- ISSN
- 18846580
- 00373826
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- HANDLE
- 10091/16040
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- NDL書誌ID
- 024052799
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可