爪白せんの外用療法 40%尿素含有ビフォナゾールクリームによる密封療法の有用性について

DOI オープンアクセス

書誌事項

タイトル別名
  • Topical Treatment of Onychomycosis with Bifonazole Cream Containing 40% Urea.

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説明

Onychomycosis patients were treated topically with bifonazole-urea cream. This cream, prepared in our hospital, was composed of 0.6% bifonazole, 40% urea and 3% carboxymethylcellulose cream. Bifonazole-urea cream was applied to the infected nails, which were then covered with occlusive dressing, left overnight, washed and then further treated by application of 1% bifonazole solution. Softened, affected lesions were removed with a nail file or nail clipper. Fifty patients, positive for mycelium by direct examination, were prescribed this treatment, with forty being followed up for twelve weeks. Twenty-six out of the forty patients (65.0%) appeared to be mycologically negative after an average of 60 days' treatment. Local irritation was observed as a side effect in only one of the 50 cases. The cream with the above-mentioned formula was found to be effective both for patients who had griseofulvin-resistant onychomycosis and those with systemic diseases who could not tolerate griseofulvin treatment. This data suggests that this formula is very useful as a topical treatment for onychomycosis.

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詳細情報 詳細情報について

  • CRID
    1390001204212708736
  • NII論文ID
    130003671775
  • DOI
    10.3314/jjmm.35.281
  • ISSN
    18820476
    09164804
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
    • OpenAIRE
  • 抄録ライセンスフラグ
    使用不可

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