<I>CLOSTRIDIUM DIFFICILE</I> COLITIS SHOWED AN APHTHOID EROSION WITHOUT ANY PSEUDOMEMBRANOUS LESION

  • UEDA Wataru
    Department of Gastroenterology, Osaka City General Hospital. Department of Gastroenterology, Osaka City Juso Hospital.
  • ARIMOTO Yuki
    Department of Gastroenterology, Osaka City General Hospital. Department of Gastroenterology, Osaka City Juso Hospital.
  • TANAKA Toshihiro
    Department of Gastroenterology, Osaka City General Hospital. Department of Gastroenterology and Hepatology, Kansai Medical University.
  • KOTANI Kohei
    Department of Gastroenterology, Osaka City General Hospital. Department of Nuclear Medicine, Osaka City University.
  • MATSUI Saori
    Department of Gastroenterology, Osaka City General Hospital. Department of Gastroenterology, Yodogawa Christian Hospital.
  • SANO Koji
    Department of Gastroenterology, Osaka City General Hospital.
  • KUBO Yuki
    Department of Pathollogy, Osaka City General Hospital.
  • INOUE Takeshi
    Department of Pathollogy, Osaka City General Hospital.
  • AOKI Tetsuya
    Department of Gastroenterology, Osaka City Juso Hospital.
  • OKAWA Kiyotaka
    Department of Gastroenterology, Osaka City General Hospital. Department of Gastroenterology, Osaka City Juso Hospital.

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Other Title
  • アフタを呈した<I>Clostridium difficile</I>腸炎の臨床的検討

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Abstract

The endoscopic diagnosis of Clostridium difficile colitis(CDC) with the existence of a pseudomembrane has been well-recognized, but the endoscopic images of CDC have been varied. We should therefore not persist in basing the diagnosis of CDC on the finding of the pseudomembrane. In the present study we report on 9 cases of CDC which showed an aphthoid erosion, but without any pseudomembranous lesion. However the meaning of the existence of an aphthoid erosion in CDC is not clear, and we thus investigated these 9 cases to elicit any such significance. The clinical manifestations of CDC with aphthoid erosions were mild, so that the presence of an aphthoid erosion indicated a mild case of CDC. When in doubt regarding a diagnosis of CDC with an aphthoid erosion without a pseudomembranous lesion, we should perform anaerobic cultures to identify the CDC-related toxin to confirm the diagnosis and decide on the treatment.

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